MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma

  title={MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma},
  author={Wen Wang and L J Zhao and Ye-xiong Tan and H. C. Ren and Zhong-tian Qi},
The deregulation of microRNA (miRNA) is frequently associated with a variety of cancers, including hepatocellular carcinoma (HCC). In this study, we identified 10 upregulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p and miR-518a-3p) and 10 downregulated miRNAs (miR-138, miR-214, miR-214#, miR-27a#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-5p and miR-483-3p) by Taqman miRNAs array and quantitative real-time PCR (qRT-PCR… CONTINUE READING


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