MiR-137 inhibited inflammatory response and apoptosis after spinal cord injury via targeting of MK2.

@article{Gao2018MiR137II,
  title={MiR-137 inhibited inflammatory response and apoptosis after spinal cord injury via targeting of MK2.},
  author={Lin Gao and Chenfei Dai and Zhiping Feng and Lixin Zhang and Zhiqiang Zhang},
  journal={Journal of cellular biochemistry},
  year={2018},
  volume={119 4},
  pages={
          3280-3292
        }
}
Spinal cord injuries are common and troublesome disorder, which is mediated by various signal pathways and mechanisms. MK2 is also involved in numerous inflammatory diseases including spinal cord injury. The role of microRNA-137 (miR-137) and its detailed working mechanism in spinal cord injuries remain unclear. In the present study, we found that an elevated MK2 but a decreased miR-137 was expressed in serum specimens of patients with spinal cord injury and in hydrogen peroxide-treated C8-D1A… CONTINUE READING
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