MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium

@inproceedings{Cerutti2017MiR126AM,
  title={MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium},
  author={Camilla Cerutti and Laura J. Edwards and Helga Eveline de Vries and Basil Sharrack and David Kingsley Male and Ignacio Andres Romero},
  booktitle={Scientific reports},
  year={2017}
}
Leukocyte adhesion to brain endothelial cells, the blood-brain barrier main component, is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Leukocyte adhesion is mediated mainly by selectins, cell adhesion molecules and chemokines induced by pro-inflammatory cytokines such as TNFα and IFNγ, but the regulation of this process is not fully clear. This study investigated the regulation of firm leukocyte adhesion to human brain endothelium by two… CONTINUE READING
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