MiR-124 acts as a target for Alzheimer’s disease by regulating BACE1

Abstract

Although large numbers of microRNAs (miRNAs) expressed in Alzheimer disease (AD) have been detected, their functions and mechanisms of regulation remain to be fully clarified. Beta-site Amyloid precursor protein Cleaving Enzyme 1 (BACE1) has been one of the prime therapeutic targets for AD. Here, we identified that miR-124 levels are gradually decreased in… (More)
DOI: 10.18632/oncotarget.23119

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