MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia

@article{Zheng2012MiR100RC,
  title={MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia},
  author={Y-S Zheng and Haibo Zhang and X-J Zhang and Dan-dan Feng and X-Q Luo and Cheng-Wu Zeng and K Y Lin and H. Zhou and Liang-Hu Qu and P. Zhang and Y-Q Chen},
  journal={Oncogene},
  year={2012},
  volume={31},
  pages={80 - 92}
}
Acute myeloblastic leukemia (AML) is characterized by the accumulation of abnormal myeloblasts (mainly granulocyte or monocyte precursors) in the bone marrow and blood. Though great progress has been made for improvement in clinical treatment during the past decades, only minority with AML achieve long-term survival. Therefore, further understanding mechanisms of leukemogenesis and exploring novel therapeutic strategies are still crucial for improving disease outcome. MicroRNA-100 (miR-100), a… Expand
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