MiR‐145 inhibits human colorectal cancer cell migration and invasion via PAK4‐dependent pathway

@inproceedings{Sheng2017MiR145IH,
  title={MiR‐145 inhibits human colorectal cancer cell migration and invasion via PAK4‐dependent pathway},
  author={Nengquan Sheng and Gewen Tan and Weiqiang You and Hongqi Chen and Jianfeng Gong and Di Chen and Hui-Zhen Zhang and Zhigang Wang},
  booktitle={Cancer medicine},
  year={2017}
}
MicroRNA-145 (miR-145), as a tumor-suppressive miRNA, has been demonstrated down-regulated in colorectal cancer (CRC) cells, and could inhibit CRC cells growth. However, the molecular pathway in which miR-145 modulates CRC malignant transformation has not been fully revealed. Here, we reported an intense correlation between the expressions of PAK4 and miR… CONTINUE READING