Mg deficiency results in modulation of serum lipids, glutathione, and NO synthase isozyme activation in cardiovascular tissues: relevance to de novo synthesis of ceramide, serum Mg and atherogenesis.

@article{Shah2011MgDR,
  title={Mg deficiency results in modulation of serum lipids, glutathione, and NO synthase isozyme activation in cardiovascular tissues: relevance to de novo synthesis of ceramide, serum Mg and atherogenesis.},
  author={Nilank C. Shah and Jian-ping Liu and Jahangir Iqbal and M. Mahmood Hussain and Xian-cheng Jiang and Zhiqiang Li and Yan Li and Tao Zheng and Wenyan Li and Anthony C Sica and Jos{\'e} Luis Perez-Albela and Bella T. Altura and B. Mauricio Altura},
  journal={International journal of clinical and experimental medicine},
  year={2011},
  volume={4 2},
  pages={
          103-18
        }
}
The present work tested the hypothesis that short-term (S-T) dietary deficiency of magnesium (Mg) (21 days) in rats would: 1) result in reduction in serum(s) sphingomyelin (SM) and changes in several blood lipids, HDL-cholesterol (HDL-C) and phosphatidylcholine (PC) concomitant with elevations in s cholesterol (chol), s LDL+VLDL and trigycerides (TG), as well as reduction in the PC/cholesterol ratio; 2) lead to oxidative stress, characterized by reductions in glutathione (glut) content in the… CONTINUE READING

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