Mfa4, an Accessory Protein of Mfa1 Fimbriae, Modulates Fimbrial Biogenesis, Cell Auto-Aggregation, and Biofilm Formation in Porphyromonas gingivalis

@inproceedings{Ikai2015Mfa4AA,
  title={Mfa4, an Accessory Protein of Mfa1 Fimbriae, Modulates Fimbrial Biogenesis, Cell Auto-Aggregation, and Biofilm Formation in Porphyromonas gingivalis},
  author={Ryota Ikai and Yoshiaki Hasegawa and Masashi Izumigawa and Keiji Nagano and Yasuo Yoshida and Noriyuki Kitai and Richard J Lamont and Fuminobu Yoshimura and Yukitaka Murakami and Christopher V. Rao},
  booktitle={PloS one},
  year={2015}
}
Porphyromonas gingivalis, a gram-negative obligate anaerobic bacterium, is considered to be a key pathogen in periodontal disease. The bacterium expresses Mfa1 fimbriae, which are composed of polymers of Mfa1. The minor accessory components Mfa3, Mfa4, and Mfa5 are incorporated into these fimbriae. In this study, we characterized Mfa4 using genetically modified strains. Deficiency in the mfa4 gene decreased, but did not eliminate, expression of Mfa1 fimbriae. However, Mfa3 and Mfa5 were not… CONTINUE READING

Citations

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SHOWING 1-10 OF 12 CITATIONS

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  • Journal of dental research
  • 2016
VIEW 11 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Maturation of the Mfa1 Fimbriae in the Oral Pathogen Porphyromonas gingivalis

  • Front. Cell. Infect. Microbiol.
  • 2018
VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Characterization of Porphyromonas gingivalis Mfa1 fimbriae.

VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Porphyromonas gingivalis fimbriae: Recent findings of downstream products ofmfa1 gene cluster

Y Hasegawa, Y. Murakami
  • J Oral Biosci
  • 2014
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Subversion of innate immunity by periodontopathic bacteria via exploitation of complement receptor-3.

  • Advances in experimental medicine and biology
  • 2008
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

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