Mexican Trypanosoma cruzi T. cruzi I Strains with Different Degrees of Virulence Induce Diverse Humoral and Cellular Immune Responses in a Murine Experimental Infection Model

@inproceedings{Espinoza2010MexicanTC,
  title={Mexican Trypanosoma cruzi T. cruzi I  Strains with Different Degrees of Virulence Induce Diverse Humoral and Cellular Immune Responses in a Murine Experimental Infection Model},
  author={Bertha Espinoza and T. Rico and Souad Sosa and E. Oaxaca and Andrea Vizca{\'i}no-Castillo and Mar{\'i}a Luisa Caballero and Ignacio Gonz{\'a}lez Mart{\'i}nez},
  booktitle={Journal of biomedicine & biotechnology},
  year={2010}
}
It is has been shown that the majority of T. cruzi strains isolated from Mexico belong to the T. cruzi I (TCI). The immune response produced in response to Mexican T. cruzi I strains has not been well characterized. In this study, two Mexican T. cruzi I strains were used to infect Balb/c mice. The Queretaro (TBAR/MX/0000/Queretaro)(Qro) strain resulted in 100% mortality. In contrast, no mortality was observed in mice infected with the Ninoa (MHOM/MX/1994/Ninoa) strain. Both strains produced… CONTINUE READING
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