MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa.

@article{Jin2011MexTRT,
  title={MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa.},
  author={Yongxin Jin and Hongjiang Yang and M. Qiao and Shouguang Jin},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 2},
  pages={399-410}
}
The type III secretion system (T3SS) is the most important virulence factor in Pseudomonas aeruginosa, and its expression level varies in different isolates. We studied the molecular basis for such differences in two laboratory strains, PAK and PAO1. A chromosomal clone library from the high-T3SS-producer strain PAK was introduced into the low-producer strain PAO1, and we found that a mexS gene from PAK confers high T3SS expression in the PAO1 background. Further tests demonstrated that both… CONTINUE READING
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