Mevalonate pyrophosphate decarboxylase is predominantly located in the cytosol of rat hepatocytes.

@article{Michihara2001MevalonatePD,
  title={Mevalonate pyrophosphate decarboxylase is predominantly located in the cytosol of rat hepatocytes.},
  author={Akihiro Michihara and Makoto Sawamura and Yukio Yamori and Kenji Akasaki and Hiroshi Tsuji},
  journal={Biological & pharmaceutical bulletin},
  year={2001},
  volume={24 11},
  pages={1235-40}
}
Mevalonate pyrophosphate decarboxylase (MPD) is found in the 100000 x g supernatant fraction of cells or tissues and is considered to be a cytosolic protein. Recently, other groups reported that MPD is mostly located in the peroxisomes. In this study, we used two different methods to determine whether MPD is predominantly located in the peroxisomes or the… CONTINUE READING