Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer.

Abstract

Metronomic chemotherapy is the frequent administration of low doses of chemotherapeutic agents targeting tumor-associated endothelial cells. We examined the efficacy of metronomic taxanes alone and in combination with AEE788-a dual epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR) inhibitor-in an orthotopic… (More)

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@article{Kamat2007MetronomicCE, title={Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer.}, author={Aparna A Kamat and Tae Jin Kim and Charles N. Landen and Chunhua Lu and Liz Y. Han and Yvonne Gail Lin and William M. Merritt and Premal H. Thaker and David M. Gershenson and Farideh Z. Bischoff and John V. Heymach and Robert B. Jaffe and Robert L. Coleman and Anil K. Sood}, journal={Cancer research}, year={2007}, volume={67 1}, pages={281-8} }