Metronidazole-deoxybenzoin derivatives as anti-Helicobacter pylori agents with potent inhibitory activity against HPE-induced interleukin-8.

Abstract

A series of new metronidazole-deoxybenzoin derivatives were synthesized and evaluated for their antimicrobial activity against Helicobacter pylori. Highly selective anti-H. pylori activity was also observed in synthesized compounds. Compound 34 exhibited the most potent activity, similar to the positive control amoxicillin. Furthermore, compounds 17 and 34… (More)
DOI: 10.1002/cmdc.201000126

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Cite this paper

@article{Luo2010MetronidazoledeoxybenzoinDA, title={Metronidazole-deoxybenzoin derivatives as anti-Helicobacter pylori agents with potent inhibitory activity against HPE-induced interleukin-8.}, author={Yin Luo and H F Li and Yang Zhou and Zi-Lin Li and Tao Yan and Hailiang L. Zhu}, journal={ChemMedChem}, year={2010}, volume={5 7}, pages={1110-6} }