Metoprolol and propranolol in migraine prophylaxis: a double-blind multicentre study.

@article{Olsson1984MetoprololAP,
  title={Metoprolol and propranolol in migraine prophylaxis: a double-blind multicentre study.},
  author={J E Olsson and H C Behring and B Forssman and C Hedman and G E Hedman and Folke Johansson and J E Kinnman and Sven E. P{\aa}lhagen and Malin Samuelsson and Eva Strandman},
  journal={Acta neurologica Scandinavica},
  year={1984},
  volume={70 3},
  pages={160-8}
}
In a double-blind, cross-over multicentre trial, the prophylactic antimigraine effect of the beta 1-selective beta-blocker metoprolol was evaluated and compared with that of the non-selective beta-blocker propranolol. Metoprolol was used in a dosage of 50 mg b.i.d. and propranolol in 40 mg b.i.d. 56 patients with classical or common migraine were included in the double-blind part of the investigation. 3 patients withdrew, but none because of side-effects. The data suggest that metoprolol is… CONTINUE READING