Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study

  title={Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study},
  author={Laura Garc{\'i}a-{\'A}lvarez and Matthew T. G. Holden and Heather Lindsay and Cerian R Webb and Derek F. J. Brown and Martin David Curran and Enid Walpole and Karen L. Brooks and Derek John Juan Pickard and Christopher J Teale and Julian Parkhill and Stephen D. Bentley and Giles F. S. Edwards and E Kirsty Girvan and Angela M. Kearns and Bruno Pichon and Robert R. Hill and Anders Rhod Larsen and Robert L Skov and Sharon J Peacock and Duncan J Maskell and Mark A Holmes},
  booktitle={The Lancet. Infectious diseases},
BACKGROUND Animals can act as a reservoir and source for the emergence of novel meticillin-resistant Staphylococcus aureus (MRSA) clones in human beings. Here, we report the discovery of a strain of S aureus (LGA251) isolated from bulk milk that was phenotypically resistant to meticillin but tested negative for the mecA gene and a preliminary investigation of the extent to which such strains are present in bovine and human populations. METHODS Isolates of bovine MRSA were obtained from the… CONTINUE READING
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