Methylthioxylose--a jewel in the mycobacterial crown?


Ten years ago an unusual sugar was discovered in a cell wall polysaccharide of Mycobacterium tuberculosis. Structural elucidation revealed the presence of the first thiosugar in a bacterial polysaccharide. Synthetic studies have helped to define its relative and absolute configuration as α-D-methylthioxylofuranosyl. While its biosynthetic origins remain the subject of speculation, work has begun to define its possible biological roles.

DOI: 10.1039/c2ob25630d

Cite this paper

@article{Turnbull2012MethylthioxyloseaJI, title={Methylthioxylose--a jewel in the mycobacterial crown?}, author={W Bruce Turnbull and Susanne A Stalford}, journal={Organic & biomolecular chemistry}, year={2012}, volume={10 30}, pages={5698-706} }