Methyltestosterone efficiently induces male development in the self-fertilizing hermaphrodite fish, Kryptolebias marmoratus.

@article{Kanamori2006MethyltestosteroneEI,
  title={Methyltestosterone efficiently induces male development in the self-fertilizing hermaphrodite fish, Kryptolebias marmoratus.},
  author={Akira Kanamori and Aki Yamamura and Satoshi Koshiba and Jae-Seong Lee and Edward F. Orlando and H. Hori},
  journal={Genesis},
  year={2006},
  volume={44 10},
  pages={
          495-503
        }
}
A hermaphrodite fish, Kryptolebias marmoratus, is the only known vertebrate that reproduces by self-fertilization. In nature, males have been rarely observed. Low-temperature treatment during late embryonic stages is known to induce males but its efficacy is variable. Here we report that 17alpha-methyltestosterone (MT) treatment of the embryos converted most of the fish to males. We examined a time course of this male induction with histological and marker gene expression analyses. Oogenesis… CONTINUE READING
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