Methylprednisolone pulse therapy in the treatment of severe forms of Schönlein-Henoch purpura nephritis

  title={Methylprednisolone pulse therapy in the treatment of severe forms of Sch{\"o}nlein-Henoch purpura nephritis},
  author={Patrick Niaudet and Ren{\'e}e Habib},
  journal={Pediatric Nephrology},
 Between 1980 and 1994, 38 children with severe forms of Schönlein-Henoch purpura glomerulonephritis were entered into a prospective study to evaluate methylprednisolone pulse therapy on the outcome of nephropathy in terms of clinical symptoms and histopathological changes. The patients were considered at risk of developing chronic renal failure when they presented with a nephrotic syndrome and/or had 50% or more crescentic glomeruli. Initial renal biopsies were obtained from all patients and… CONTINUE READING
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