Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial.

@article{Meduri2007MethylprednisoloneII,
  title={Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial.},
  author={Gianfranco Umberto Meduri and E Golden and Amado Xavier Freire and Edwin W. Taylor and Muhammad Badrus Zaman and Stephanie J. Carson and Mary Hope Gibson and Reba Umberger},
  journal={Chest},
  year={2007},
  volume={131 4},
  pages={
          954-63
        }
}
OBJECTIVE To determine the effects of low-dose prolonged methylprednisolone infusion on lung function in patients with early severe ARDS. DESIGN Randomized, double-blind, placebo-controlled trial. SETTING ICUs of five hospitals in Memphis. PARTICIPANTS Ninety-one patients with severe early ARDS (</= 72 h), 66% with sepsis. INTERVENTIONS Patients were randomized (2:1 fashion) to methylprednisolone infusion (1 mg/kg/d) vs placebo. The duration of treatment was up to 28 days. Infection… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 18 REFERENCES

Comparison among means : planned comparisons . Biometry , The principles and practices of statistics in biological research

HA Kahn, CT Sempos
  • The principles and practices of statistics in biological research
  • 1998

Comparison among means: planned comparisons. Biometry, The principles and practices of statistics in biological research. The principles and practices of statistics in biological research

RR F. Sokal
  • 1998
VIEW 1 EXCERPT