Methylprednisolone in multiple sclerosis: a comparison of oral with intravenous therapy at equivalent high dose.

@article{Alam1993MethylprednisoloneIM,
  title={Methylprednisolone in multiple sclerosis: a comparison of oral with intravenous therapy at equivalent high dose.},
  author={Shama Alam and Th Kyriakides and Mark C Lawden and Peter K Newman},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={1993},
  volume={56 11},
  pages={1219-20}
}
A randomised double-blind placebo-controlled trial of intravenous methylprednisolone versus oral methylprednisolone at equivalent high dose was carried out on 35 patients with an acute relapse of multiple sclerosis (MS). After baseline evaluation each was randomly allocated to oral treatment and intravenous placebo or intravenous treatment and oral placebo, receiving 500 mg of methylprednisolone for five consecutive days and with reassessment at days five and twenty-eight. There was no… CONTINUE READING

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A double blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis . 1 . Clinical effects

  • NM Milligan, R Newcombe, Compston DAS
  • J Neurol Neurosurg Psychiatry
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