Methylphenidate hydrochloride given with or before breakfast: I. Behavioral, cognitive, and electrophysiologic effects.

@article{Swanson1983MethylphenidateHG,
  title={Methylphenidate hydrochloride given with or before breakfast: I. Behavioral, cognitive, and electrophysiologic effects.},
  author={James M. Swanson and Curt A. Sandman and Carol Deutsch and M Baren},
  journal={Pediatrics},
  year={1983},
  volume={72 1},
  pages={49-55}
}
Methylphenidate HCl (Ritalin) is usually given for the treatment of hyperactivity or attention deficit disorder (ADD) at 30 minutes to one hour before meals. This schedule is based on the assumption that, when taken with meals, its absorption or metabolism is altered. However, no behavioral or pharmacologic data exist to support this recommendation. Eleven patients with attention deficit disorder were tested to evaluate this hypothesis using a double-blind crossover design (methylphenidate with… CONTINUE READING

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