Methylphenidate blocks effort-induced depletion of regulatory control in healthy volunteers.

@article{Sripada2014MethylphenidateBE,
  title={Methylphenidate blocks effort-induced depletion of regulatory control in healthy volunteers.},
  author={Chandra Sekhar Sripada and Daniel Kessler and John Jonides},
  journal={Psychological science},
  year={2014},
  volume={25 6},
  pages={1227-34}
}
A recent wave of studies--more than 100 conducted over the last decade--has shown that exerting effort at controlling impulses or behavioral tendencies leaves a person depleted and less able to engage in subsequent rounds of regulation. Regulatory depletion is thought to play an important role in everyday problems (e.g., excessive spending, overeating) as well as psychiatric conditions, but its neurophysiological basis is poorly understood. Using a placebo-controlled, double-blind design, we… CONTINUE READING
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