Methylphenidate and its Isomers

@article{Heal2006MethylphenidateAI,
  title={Methylphenidate and its Isomers},
  author={David J. Heal and David Montague Pierce},
  journal={CNS Drugs},
  year={2006},
  volume={20},
  pages={713-738}
}
Abstractdl-threo-Methylphenidate is a highly efficacious drug for treating attention-deficit hyperactivity disorder (ADHD) that is currently administered as immediate- or controlled-release and osmotically controlled-released formulations. The drug exists as two enantiomers, d-threo-methylphenidate and l-threo-methylphenidate, with the former having been developed as a medication to treat ADHD in its own right. dl-threo-Methylphenidate undergoes enantioselective metabolism in the liver, which… 

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