Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model

@inproceedings{AgaMizrachi2014MethylphenidateAD,
  title={Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model},
  author={S Aga-Mizrachi and A Cymerblit-Sabba and Oyku Gurman and Anita Balan and G Shwam and R Deshe and Lee E. Miller and Nady Gorodetsky and Norbert Heinrich and O Tzezana and Salman Zubedat and Dan Grinstein and Avi Avital},
  booktitle={Translational Psychiatry},
  year={2014}
}
Antidepressant medication constitutes the first line pharmacological treatment for posttraumatic stress disorder (PTSD), however, because many patients display no beneficial drug effects it has been suggested that combinations of antidepressants with additional drugs may be necessary. The defining symptoms of PTSD include re-experiencing, avoidance and hyperarousal. In addition, PTSD patients were shown to become easily distracted and often suffer from poor concentration together with… CONTINUE READING
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Interaction between methylphenidate, methadone and different antidepressant drugs on antinociception in mice, and possible clinical implications.

  • The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • 2017
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