Methylphenidate and atomoxetine normalise fronto-parietal underactivation during sustained attention in ADHD adolescents

@article{Kowalczyk2019MethylphenidateAA,
  title={Methylphenidate and atomoxetine normalise fronto-parietal underactivation during sustained attention in ADHD adolescents},
  author={Olivia S. Kowalczyk and A Cubillo and Anna B. Smith and Nadia Barrett and Vincent Giampietro and Michael J. Brammer and Andrew Simmons and Katya Rubia},
  journal={European Neuropsychopharmacology},
  year={2019},
  volume={29},
  pages={1102-1116}
}
Problems with sustained attention are a key clinical feature of Attention Deficit/Hyperactivity Disorder (ADHD) which also manifests in poor performance and abnormal fronto-striato-parietal activation during sustained attention. Methylphenidate and atomoxetine improve attention functions and upregulate abnormal fronto-cortical activation during executive function tasks in ADHD patients. Despite this, no functional Magnetic Resonance Imaging (fMRI) study has compared the effects of… Expand
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