Methylphenidate and amantadine to stimulate reawakening in comatose patients resuscitated from cardiac arrest.

@article{Reynolds2013MethylphenidateAA,
  title={Methylphenidate and amantadine to stimulate reawakening in comatose patients resuscitated from cardiac arrest.},
  author={Joshua C. Reynolds and J C Rittenberger and Clifton Callaway},
  journal={Resuscitation},
  year={2013},
  volume={84 6},
  pages={818-24}
}
BACKGROUND Despite critical-care packages including therapeutic hypothermia (TH), neurologic injury is common after cardiac arrest (CA) resuscitation. Methylphenidate and amantadine have treated coma in traumatically-brain-injured patients with mixed success, but have not been explored in post-arrest patients. OBJECTIVE Compare the outcome of comatose post-arrest patients treated with neurostimulants to a matched cohort. METHODS Retrospective cohort study from 6/2008 to 12/2011 in a… CONTINUE READING
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