Methylphenidate Normalizes Frontocingulate Underactivation During Error Processing in Attention-Deficit/Hyperactivity Disorder

@inproceedings{Rubia2011MethylphenidateNF,
  title={Methylphenidate Normalizes Frontocingulate Underactivation During Error Processing in Attention-Deficit/Hyperactivity Disorder},
  author={Katya Rubia and Rozmin Halari and Abdul-Majeed Mohammad and Eric A. Taylor and Michael J. Brammer},
  booktitle={Biological Psychiatry},
  year={2011}
}
BACKGROUND Children with attention-deficit/hyperactivity disorder (ADHD) have deficits in performance monitoring often improved with the indirect catecholamine agonist methylphenidate (MPH). We used functional magnetic resonance imaging to investigate the effects of single-dose MPH on activation of error processing brain areas in medication-naive boys with ADHD during a stop task that elicits 50% error rates. METHODS Twelve medication-naive boys with ADHD were scanned twice, under either a… CONTINUE READING

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