Methylphenidate-Induced Psychosis in Adult Attention-Deficit/Hyperactivity Disorder: Report of 3 New Cases and Review of the Literature
@article{Kraemer2010MethylphenidateInducedPI, title={Methylphenidate-Induced Psychosis in Adult Attention-Deficit/Hyperactivity Disorder: Report of 3 New Cases and Review of the Literature}, author={M Kraemer and Jennifer Uekermann and Jens Wiltfang and Bernhard Kis}, journal={Clinical Neuropharmacology}, year={2010}, volume={33}, pages={204-206} }
Objective:We present 3 new cases of psychotic symptoms in patients with adult attention-deficit/hyperactivity disorder while regularly treated with a stimulant therapy with methylphenidate. Methods:Existing literature about this theme is reviewed, and potential mechanisms are discussed. Results and Conclusions:Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a…
56 Citations
Methylphenidate induced acute psychosis in a case with mild intellectual disability and ADHD
- Medicine, Psychology
- 2018
A case of 11 years old boy with diagnosis of ADHD and mild intellectual disability, who was treated with methylphenidate and later developed acute psychosis is described.
Methylphenidate Induced Psychotic Symptoms: Two Cases Report
- Psychology, Medicine
- 2013
Two cases were reported who diagnosed with ADHD, and shortly after the beginning of the long-acting metylphenidate treatment psychotic symptoms has emerged, and it was discussed the treatment process of the psychotic symptoms.
Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate.
- Medicine, PsychologyGeneral hospital psychiatry
- 2013
Reintroduction of stimulant treatment for patients with ADHD, after stimulant-related psychosis
- Psychology, Medicine
- 2014
Three additional cases where rechallenging with stimulant medication did not result in reappearance of psychotic symptoms are reported, and possible risk factors for developing such side effects and hypothesized mechanisms are discussed.
Methylphenidate-Induced Psychotic Symptoms in 65-Year-Old Female with ADHD
- Psychology, MedicineIranian journal of psychiatry
- 2018
This case presents psychotic manifestations due to methylphenidate in a 65-year-old female who was taking this medication for ADHD who thought that they were sleeping pills and was discontinued which resulted in improvement of her psychosis.
Methylphenidate for psychosis and aggression in a patient comorbid with ADHD - A case report.
- Psychology, MedicinePsychiatria Danubina
- 2014
While caring for a patient with comorbidity of ADHS and psychosis the authors were not able to find guidelines or treatment recommendations issued by a major society concerning state of the art treatment of such a case.
An update on the safety of psychostimulants for the treatment of attention-deficit/hyperactivity disorder
- Psychology, MedicineExpert opinion on drug safety
- 2017
Although methylphenidate has a well-established evidence base for treating ADHD, its long-term benefits are unclear and much less is known about longer-term efficacy and safety of these drugs.
Aripiprazole Treatment in a Patient with Schizophrenia and Severe Antipsychotic-Induced Parkinsonism Following Long-Term use of Methylphenidate: A Case Report
- Psychology, Medicine
- 2016
The present case report cautiously suggests the possible value of aripiprazole's stabilizing qualities as a treatment for attention-deficit/hyperactivity disorder.
Does amantadine induce acute psychosis? A case report and literature review
- Medicine, PsychologyNeuropsychiatric disease and treatment
- 2016
Clinicians should be sensitive to the acute psychotic complications induced by an interaction between amantadine and acetaminophen.
Detecting and treating adult attention deficit hyperactivity disorder in a patient with schizophrenia
- Psychology, Medicineneuropsychiatrie
- 2014
It is indicated that atomoxetine may be effective in treating symptoms of ADHD in patients with schizophrenia, without increasing psychotic symptoms.
References
SHOWING 1-10 OF 24 REFERENCES
[Drug-induced psychosis after intake of a modified--release formulation of methylphenidate].
- Medicine, PsychologyPsychiatrische Praxis
- 2009
It is concluded that the ingestion of an unintended overdose ofmethylphenidate may have caused the boy's psychotic symptoms and that routine therapeutic serum concentrations of methylphenidate have to be correlated to the point of time when the blood was drawn in relation to the intake ofethylphenidate.
Attention-deficit hyperactivity disorder and comorbid psychosis: a review and two clinical presentations.
- Psychology, MedicineThe Journal of clinical psychiatry
- 1993
It is suggested that further attention be given to the evaluation, treatment, and eventual classification of a potentially distinct patient group with ADHD and atypical psychotic episodes.
Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action.
- Psychology, Medicine
- 1981
It is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated and two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation of transmission of information in the visual pathway, and (2) interactions among brain monoamine systems.
Psychotic and manic-like symptoms during stimulant treatment of attention deficit hyperactivity disorder.
- Psychology, MedicineThe American journal of psychiatry
- 2006
A boy 6 years 9 months of age was brought by his mother to a child psychiatrist for difficulties with sustained attention, distraction, careless errors, poor listening, difficulty following…
Schizophrenia and narcolepsy: A review with a case report
- Psychology, MedicinePsychiatry and clinical neurosciences
- 2004
The present case report describes a difficult‐to‐treat patient who likely had concurrent schizophrenia and narcolepsy and summarizes the literature related to the treatment of the three types of patients with psychosis associated with narcoLEpsy.
Attention-deficit/hyperactivity disorder and the substance use disorders: the nature of the relationship, subtypes at risk, and treatment issues.
- Psychology, MedicineThe Psychiatric clinics of North America
- 2004
A clinical perspective of attention-deficit/hyperactivity disorder into adulthood.
- Psychology, MedicineThe Journal of clinical psychiatry
- 2004
A growing literature indicates that ADHD is more persistent than previously thought and has a developmental variability in its presentation, which suggests the importance of short- and long-term management of the disorder.
Methylphenidate‐Induced Hallucinosis: Case Histories and Possible Mechanisms of Action
- Medicine, BiologyJournal of developmental and behavioral pediatrics : JDBP
- 1981
It is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated and two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation of transmission of information in the visual pathway, and (2) interactions among brain monoamine systems.
Folie à deux with methylphenidate psychosis.
- Psychology, MedicineThe Journal of nervous and mental disease
- 1972
Two cases of psychosis associated with oral and intravenous abuse of methylphenidate are reported. Most elements of the classic folie a deux are seen in their identical paranoid delusions. The wife…
Risks of high-dose stimulants in the treatment of disorders of excessive somnolence: a case-control study.
- Medicine, PsychologySleep
- 2005
This study demonstrated a significantly higher occurrence of psychosis, substance misuse, and psychiatric hospitalizations in patients using high-dose stimulants compared to those using standard doses.