Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system.

@article{Aschner1990MethylmercuryUI,
  title={Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system.},
  author={Michael Aschner and Nicole Eberle and Susan K. Goderie and Harold K. Kimelberg},
  journal={Brain research},
  year={1990},
  volume={521 1-2},
  pages={221-8}
}
The significance of the dense labeling pattern of methylmercury (MeHg) over astrocytes in areas of damaged cortex remains obscure, and the extent to which individual neurons are altered by MeHg accumulation in astrocytes is unknown. As a first step in understanding the relationship between the astrocyte and the mechanisms of MeHg's neurotoxicity, studies were directed at how MeHg is transported into cultured astrocytes. Uptake of [203Hg]MeHg in primary astrocyte cultures from neonatal rat… CONTINUE READING
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