Methylmercury induces hyaluronan synthesis in cultured human brain microvascular endothelial cells and pericytes via different mechanisms.

@article{Hirooka2017MethylmercuryIH,
  title={Methylmercury induces hyaluronan synthesis in cultured human brain microvascular endothelial cells and pericytes via different mechanisms.},
  author={Takashi Hirooka and Eiko Yoshida and Komyo Eto and Toshiyuki Kaji},
  journal={The Journal of toxicological sciences},
  year={2017},
  volume={42 3},
  pages={329-333}
}
In a cerebrum damaged by methylmercury, where neuropathological lesions tend to localize along deep sulci and fissures, edematous changes in white matter have been proposed as the cause of such localization. Since hyaluronan has a high water-retention capability and can contribute to the progression of edematous changes, we hypothesize that methylmercury… CONTINUE READING