Methylmercury-induced depression of neuromuscular transmission in the rat.

Abstract

Effects of bath applied methylmercury on neuromuscular transmission were assessed in the isolated phrenic nerve-hemidiaphragm of adult male rats using conventional microelectrode recording techniques. At concentrations of 20 and 100 microM, methylmercury increased the frequency of miniature end-plate potentials (MEPPs) from control values of 0.3-0.8/sec to… (More)

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