Methylisothiazolinone: second 'epidemic' of isothiazolinone sensitization.

@article{Gameiro2014MethylisothiazolinoneS,
  title={Methylisothiazolinone: second 'epidemic' of isothiazolinone sensitization.},
  author={Ana Rita Gameiro and In{\^e}s Coutinho and Leonor Ramos and Margarida Gonçalo},
  journal={Contact dermatitis},
  year={2014},
  volume={70 4},
  pages={
          242-3
        }
}
Isothiazolinones are used as biocides in a wide variety of products, such as cosmetics, detergents, and industrial products. In the 1980s, a formulation with methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) was responsible for an allergic contact dermatitis ‘epidemic’. To control this phenomenon, a maximum allowed dose was set. However in 2005, MI alone was introduced in cosmetics, and this was followed by a new ‘epidemic’ of sensitization to MI and MCI/MI (1). We performed a… CONTINUE READING

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