Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms.

@article{Xiao2010MethylerythritolC,
  title={Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms.},
  author={Youli Xiao and Rodney L Nyland and Caren L. Freel Meyers and Pinghua Liu},
  journal={Chemical communications},
  year={2010},
  volume={46 38},
  pages={7220-2}
}
In this communication, we reported another unique IspG-catalyzed transformation, the production of its substrate, MEcPP, from (2R,3R)-4-hydroxy-3-methyl-2,3-epoxybutanyl diphosphate (Epoxy-HMBPP) when reductants are excluded from the reaction mixture.