Methylenedioxymethamphetamine (MDMA, ‘Ecstasy‘) Serves as a Robust Positive Reinforcer in a Rat Runway Procedure

@article{Wakonigg2003Methylenedioxymethamphetamine,
  title={Methylenedioxymethamphetamine (MDMA, ‘Ecstasy‘) Serves as a Robust Positive Reinforcer in a Rat Runway Procedure},
  author={G. Wakonigg and Katja Sturm and A. Saria and G. Zernig},
  journal={Pharmacology},
  year={2003},
  volume={69},
  pages={180 - 182}
}
Although ‘ecstasy’ (3,4-methylenedioxymethamphetamine, MDMA) is, after marijuana, the second most prevalent illegal drug of abuse in European adolescents, animal experimental evidence of MDMA’s reinforcing effect has remained scarce, particularly in the rodent model, raising questions about the robustness of MDMA’s reinforcing effect under controlled laboratory conditions. In the present rat runway study, Sprague-Dawley and Long-Evans rats were given the opportunity to run for intravenous… Expand
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