Methylene chloride induced mouse liver and lung tumours: an overview of the role of mechanistic studies in human safety assessment.

  • T. Green
  • Published 1997 in Human & experimental toxicology

Abstract

B6C3F1 mice exposed to high dose levels of methylene chloride by inhalation for 2 years had an elevated incidence of liver and lung tumours. These tumours were not increased in rats or hamsters exposed under the same or similar conditions. This paper gives an overview of research conducted over the last 10 years into the mechanism of action of methylene… (More)

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@article{Green1997MethyleneCI, title={Methylene chloride induced mouse liver and lung tumours: an overview of the role of mechanistic studies in human safety assessment.}, author={T. Green}, journal={Human & experimental toxicology}, year={1997}, volume={16 1}, pages={3-13} }