Methylene blue reduces mortality and morbidity in vasoplegic patients after cardiac surgery.

@article{Levin2004MethyleneBR,
  title={Methylene blue reduces mortality and morbidity in vasoplegic patients after cardiac surgery.},
  author={Ricardo L. Levin and Marcela A Degrange and Gustavo F Bruno and Carlos D del Mazo and Daniel J Taborda and Jorge J Griotti and Fernando J. Boullon},
  journal={The Annals of thoracic surgery},
  year={2004},
  volume={77 2},
  pages={
          496-9
        }
}
BACKGROUND The discovery of nitric oxide as mediator in cardiac postoperative vasoplegia encourages the use of inhibitory drugs such as methylene blue. This drug has been used with favorable results in isolated cases. The purpose of this article is to analyze the incidence of the postoperative vasoplegic syndrome, to consider its prognosis, and to evaluate the effect of intravenous methylene blue on mortality. METHODS Cardiac surgery patients were consecutively included. Vasoplegic syndrome… CONTINUE READING
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