Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.

Abstract

BACKGROUND Huntington's disease (HD) is a Polyglutamine disease caused by the presence of CAG repeats in the first exon of Huntingtin (Htt), a large protein with multiple functions. In addition to neurodegeneration of specific brain regions, notably the striatum, HD also shows alterations in peripheral tissues, such as the heart, skeletal muscles or… (More)
DOI: 10.3233/JHD-140130

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