Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment.

  title={Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment.},
  author={David A Basketter},
  journal={Cutaneous and ocular toxicology},
  volume={29 1},
Preservatives can be a frequent cause of allergic contact dermatitis (ACD). A quantitative risk assessment (QRA) method for identifying safe exposure levels has been suggested as a more effective tool for this purpose. This work assesses the validity of QRA by its retrospective application to the sensitizing preservative methyldibromoglutaronitrile (MDGN), which has recently been associated with unacceptable exposure levels in consumer products. Using a recently published QRA analysis of 4… CONTINUE READING


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