Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.

@article{Zhang2015MethylationPL,
  title={Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.},
  author={Xinbo Zhang and Naimei Tang and Arun K. Rishi and Harvey I. Pass and Anil Wali},
  journal={Methods in molecular biology},
  year={2015},
  volume={1238},
  pages={
          235-47
        }
}
Malignant Pleural Mesothelioma (MPM) is an aggressive malignancy of the pleura associated with asbestos exposure. Incidence of MPM is expected to increase over the course of next decade in both Europe and the developing countries. Although significant progress has been made in terms of etiology and pathogenesis of this disease, currently available therapeutic options have not significantly improved the survival outcome of patients on standard chemotherapeutic regimens. Integrity of the cellular… CONTINUE READING
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