Methylation patterns of genes coding for drug-metabolizing enzymes in tamoxifen-resistant breast cancer tissues

@article{Kim2010MethylationPO,
  title={Methylation patterns of genes coding for drug-metabolizing enzymes in tamoxifen-resistant breast cancer tissues},
  author={Sun Jung Kim and Han-Sung Kang and S Y Jung and Sun Young Min and Seeyoun Lee and Seok Won Kim and Youngmi Kwon and Keun Seok Lee and Kyung Hwan Shin and Jungsil Ro},
  journal={Journal of Molecular Medicine},
  year={2010},
  volume={88},
  pages={1123-1131}
}
The biological mechanisms underlying resistance to tamoxifen are of considerable clinical significance. However, little is known about the correlation between tamoxifen resistance and methylation of genes related to drug-metabolizing enzymes. To address this issue, we examined the methylation pattern and expression of the selected genes coding for drug… CONTINUE READING