Methylation of the HOXA10 homeobox gene promoter is associated with endometrial cancer: a pilot study.

Abstract

Methylation in the promoter region represents an epigenetic mechanism that silences expression of various homeobox genes in cancers. We compare the methylation profile of HOXA10 promoter gene in 19 histologically proven endometrioid cancers and 27 normal endometrial tissues. Endometrial cancer tissue displays significantly higher methylation status in… (More)
DOI: 10.3109/01443615.2013.776027

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