Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation

  title={Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation},
  author={Magnus E. Jakobsson and Jędrzej M. Małecki and Benedikt S Nilges and Anders Moen and Sebastian A. Leidel and P{\aa}l {\O}. Falnes},
  journal={Nucleic Acids Research},
  pages={8239 - 8254}
Abstract Many cellular proteins are methylated on lysine residues and this has been most intensively studied for histone proteins. Lysine methylations on non-histone proteins are also frequent, but in most cases the functional significance of the methylation event, as well as the identity of the responsible lysine (K) specific methyltransferase (KMT), remain unknown. Several recently discovered KMTs belong to the so-called seven-β-strand (7BS) class of MTases and we have here investigated an… 

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