Methylation of P16 in exhaled breath condensate for diagnosis of non-small cell lung cancer.

@article{Xiao2014MethylationOP,
  title={Methylation of P16 in exhaled breath condensate for diagnosis of non-small cell lung cancer.},
  author={P. J. Xiao and Jian-rong Chen and Feng Zhou and Chen-xi Lu and Qichan Yang and Guo-hua Tao and Yi-jiang Tao and Jing-liang Chen},
  journal={Lung cancer},
  year={2014},
  volume={83 1},
  pages={56-60}
}
BACKGROUND Non-small cell lung cancer is the most frequently cause of cancer-related death in the world. To explore the technical feasibility, we detected aberrant promoter methylation of P16 in exhaled breath condensate which was a new, non-invasive tool for diagnosis and screening program of NSCLC. METHODS We analyzed aberrant promoter methylation of P16 in 180 samples from 60 individuals, including 30 NSCLC patients (cancer tissues, adjacent normal lung tissues, blood plasma, and EBC), and… CONTINUE READING