Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells.

Abstract

BACKGROUND The role of selenium in reducing the risk of multiple cancers has been described in the literature. Although reports have described the antiproliferative and pro-apoptotic function of selenium by up-regulation of genes in these pathways, information is lacking on the target mechanisms of selenium on specific genes. This study examines whether… (More)

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