Methylation dynamics of imprinted genes in mouse germ cells.

@article{Lucifero2002MethylationDO,
  title={Methylation dynamics of imprinted genes in mouse germ cells.},
  author={Diana Lucifero and Carmen Mertineit and Hugh J Clarke and Timothy H Bestor and Jacquetta Trasler},
  journal={Genomics},
  year={2002},
  volume={79 4},
  pages={
          530-8
        }
}
DNA methylation differences between maternal and paternal alleles of many imprinted genes are inherited from the male and female gametes and subsequently maintained during development. However, the stages of gametogenesis during which methylation imprints are established have not been well defined. In this study, we used bisulfite sequencing to determine the methylation dynamics of the imprinted genes small nuclear ribonucleoprotein N (Snrpn), insulin-like growth factor 2 receptor (Igf2r… Expand
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TLDR
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