Methylation Protects miRNAs and siRNAs from a 3′-End Uridylation Activity in Arabidopsis


Small RNAs of 21-25 nucleotides (nt), including small interfering RNAs (siRNAs) and microRNAs (miRNAs), act as guide RNAs to silence target-gene expression in a sequence-specific manner. In addition to a Dicer homolog, DCL1, the biogenesis of miRNAs in Arabidopsis requires another protein, HEN1. miRNAs are reduced in abundance and increased in size in hen1… (More)
DOI: 10.1016/j.cub.2005.07.029


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