Methylated CpG points identified within MAGE-1 promoter are involved in gene repression.

Abstract

The MAGE-1 gene, expressed in some tumors of different histological origins, codes for a tumor antigen recognized by cytotoxic T lymphocytes. The gene is not expressed in normal tissues with the exception of testes. The present study was designed to investigate the relationship between methylation of the MAGE-1 promoter and inactivation of the MAGE-1 gene… (More)

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@article{Serrano1996MethylatedCP, title={Methylated CpG points identified within MAGE-1 promoter are involved in gene repression.}, author={Antonio Serrano and {\'A}ngel Garcia and Elva Abril and Francisco M. S. Garrido and Francisco Javier Montes Ruiz-Cabello}, journal={International journal of cancer}, year={1996}, volume={68 4}, pages={464-70} }