Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.

@article{Wang2009MethylseleniumCI,
  title={Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.},
  author={Lei Wang and Melissa J. L. Bonorden and Guang-xun Li and Hyo-Jeong Lee and Hongbo Hu and Yong Zhang and Joshua Dezhong Liao and Margot P. Cleary and Junxuan L{\"u}},
  journal={Cancer prevention research},
  year={2009},
  volume={2 5},
  pages={484-95}
}
Chemoprevention of prostate cancer by second-generation selenium compounds in reference to selenomethionine holds strong promise to deal with the disease at the root. Here we used the transgenic adenocarcinoma mouse prostate (TRAMP) model to establish the efficacy of methylseleninic acid (MSeA) and methylselenocysteine (MSeC) against prostate carcinogenesis and to characterize potential mechanisms. Eight-week-old male TRAMP mice (C57B/6 background) were given a daily oral dose of water, MSeA… CONTINUE READING
44 Citations
56 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial

  • LC Clark, GF Combs, Jr., BW Turnbull
  • Nutritional Prevention of Cancer Study Group
  • 1957
Highly Influential
4 Excerpts

Dietary 1 Unpublished data. Cancer Prevention Research 494 Cancer Prev Res 2009;2(5) May 2009 www.aacrjournals.org

  • K Raina, MJ Blouin, RP Singh
  • Cancer Research. on June
  • 2009

Similar Papers

Loading similar papers…