Methyl Mercury Toxicity in the Chick Embryo

  title={Methyl Mercury Toxicity in the Chick Embryo},
  author={Yigal Greener and Joseph A. Kochen},
  journal={Pediatric Research},
Methyl mercury (mHg) can have a devastating effect on the integrity of the nervous system. Previous studies have shown that the fetus is at particular risk. The administration of m203Hg to the pregnant rat resulted in a substantially higher level in the brains of fetuses than in the dam (12.6 ± 2.6 (9) vs 3.0μg/gm dry wt.)(M ± SD). In the chick embryo, the LD-50 for mHg injected into the yolk sac on Day 5 was 50μg. Embryos dying within 24 hours showed increased total body mHg levels when… CONTINUE READING