Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases.

@article{Gigek2016MethylCpGBindingP,
  title={Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases.},
  author={Carolina de Oliveira Gigek and Elizabeth Suchi Chen and Marilia Cardoso Smith},
  journal={Journal of cellular biochemistry},
  year={2016},
  volume={117 1},
  pages={29-38}
}
Epigenetics is the study of the heritable changes on gene expression that are responsible for the regulation of development and that have an impact on several diseases. However, it is of equal importance to understand how epigenetic machinery works. DNA methylation is the most studied epigenetic mark and is generally associated with the regulation of gene expression through the repression of promoter activity and by affecting genome stability. Therefore, the ability of the cell to interpret… CONTINUE READING

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